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Much previous work highlights the rapid increases
2019-04-19
Much previous work highlights the rapid increases in DAH in the past decade, but in , Katherine Floyd and colleagues report that, in the case of tuberculosis, growth in domestic financing has been equally impressive. Their findings are convincing, especially in view of the fact that their study migh
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adipor1 The Zika virus epidemic is spreading
2019-04-18
The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil
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TRAF as a multi functional adaptor protein can be
2019-04-18
TRAF6, as a multi-functional adaptor protein, can be rapidly activated following Toll Like Receptor 4 (TLR4) and ligand recognition [39], [40], [41], and plays an important role in inflammatory responses. Increasing evidence implied that TRAF6 is closely related to CNS diseases [42], [43]. In cerebr
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br Methods br Results The clinical genetic electrocardiograp
2019-04-18
Methods Results The clinical, genetic, electrocardiographic, and electrophysiological characteristics of the study patients are shown in Table 1. Eight of the 45 patients were symptomatic, having a history of syncope (n=3) or aborted SCD (n=5). The remaining 37 patients were asymptomatic, alth
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br Conclusions br Conflict of interest
2019-04-18
Conclusions Conflict of interest Introduction Endless loop tachycardia (ELT) is a well-recognized complication of dual chamber pacing systems [1,2]. Recent pacemaker systems adopt algorithms of ELT termination given that ELT is generally maintained at the programmed upper tracking rate. The
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clemastine br Grant support This work was supported
2019-04-18
Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20
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br Conflict of interest br Acknowledgments br
2019-04-18
Conflict of interest Acknowledgments Introduction Electroanatomical mapping is useful for locating a possible reentrant circuit, but it has limitations in terms of analyzing the functional property of the circuit [1,2]. Entrainment mapping using the postpacing interval (PPI) and the activat
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Esta parte de la cr tica a la que
2019-04-18
Esta parte de la crítica a la que aludo, en aquel entonces, se orienta hacia el replanteamiento de la función social de la literatura y el cuestionamiento epistemológico de la práctica crítica misma. Incidiendo en este aspecto, George Gugelberger llega a afirmar lo siguiente: “Thus, the testimonio b
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In a recent study Nademanee
2019-04-17
In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation
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Sin embargo no se puede hablar de etapas delimitadas con
2019-04-17
Sin embargo, no se puede hablar de etapas delimitadas con absoluta precisión; la revista Simpleton, en 1998, en un artículo que aparece sin firma, apunta que en la década de los veinte no se ignoraba si ganaría la batalla de la prosa americana el adornado estilo de Fitzgerald o la musculosa dicción
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Interim measures however are not nearly enough A massive
2019-04-17
Interim measures, however, are not nearly enough. A massive expansion of the blood donor pool is needed, but scaling up blood donation in the low-resource world is no easy task. WHO has long advocated a set of interventions to fortify a nation\'s blood supply, but countries will have difficulty solv
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Also report suggests treatment of human B cell lymphoma cell
2019-04-17
Also, report suggests, treatment of human B cell lymphoma Cy3-dUTP with etoposide, a DNA-damaging chemotherapeutic drug, activates p38 MAPK pathway but pharmacological and genetic inhibition of this pathway enhances the apoptotic effect of etoposide [105]. Likewise, doxorubicin (topoisomerase II inh
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HF is associated with the down regulation of multiple
2019-04-17
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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Herweg et al evaluated the benefit of CRT in consecutive
2019-04-17
Herweg et al. [9] evaluated the benefit of CRT in 10 consecutive patients with NYHA class IV HF who were dependent on inotropic support. Their patients had received inotropic support for 146±258 days, and all patients were alive at the mean follow-up of 1088±284 days after CRT. They also reported an
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Racial ethnic differences should also be considered for
2019-04-17
Racial/ethnic differences should also be considered for the effects of ASA. In the JAST (Japan Atrial Fibrillation Stroke Trial) in 896 Japanese patients with nonvalvular AF [22], the incidence of the primary composite endpoint (i.e., cerebral infarction, TIA, or cardiovascular death) was higher in
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