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apexbio calculator Aggressive osteoblastoma is characterized
2019-04-20
Aggressive osteoblastoma is characterized by epithelioid osteoblasts that are, two to three times larger than conventional osteoblasts, and have abundant eosinophilic cytoplasm, large vesicular eccentric round to oval nuclei with prominent nucleoli. Usually there are rare or absence of mitoses and
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Many studies over the past years have shown
2019-04-20
Many studies over the past 20 years have shown the potential of urinary markers in the detection of the presence of bone metastases [3–11], the use of urinary markers for its prognostic value in bone disease [2,4,12–20], as well as directing therapy for bone metastases patients [2,6,12–18,21–25]. Th
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br Conflict of interest br Introduction Catheter ablation is
2019-04-20
Conflict of interest Introduction Catheter ablation is an effective approach for the management of patients with atrial fibrillation (AF) [1–7]. Pulmonary vein isolation (PVI) is one of the most common strategies of AF ablation, but the outcome of PVI alone for patients with persistent AF is p
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br Ya desde el siglo xvi Salinas
2019-04-20
Ya desde el siglo xvi, Salinas parece aceptar las innovaciones de Ramos Pareja que avanzaban en el siglo xv sobre lo que sería el temperamento igual. La obra de Salinas, Siete libros sobre la música, de 1577, entabla una explícita afinidad con las teorías de su contemporáneo Zarlino, como éste nuc
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br Raising taxes on tobacco is the measure
2019-04-20
Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2
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En la segunda publicaci n
2019-04-20
En la segunda publicación, “Entrevista con don Carlos Pérez”, éste un ciudadano argentino ficticio recién llegado de Bogotá durante un viaje por Sudamérica, menciona pepstatin José María Rivas Groot a propósito de su “Estudio pre liminar”, en el Parnaso colombiano publicado en 1888 y los poetas reun
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Sin embargo la mayor a
2019-04-20
Sin embargo, la mayoría de los aventureros se quedó en la ensoñación, pues no logró hacerse de caudales, ni alcanzó encomiendas; de hecho, hacia 1540 y aun años después, el número de encomenderos en el gran Perú (hoy Perú, Bolivia y Ecuador) jamás rebasó los 500, indudablemente una minoría de la pob
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Finally it is highly interesting to note that human
2019-04-20
Finally, it is highly interesting to note that human endogenous retroviruses have been suggested to play a role in the etiology of both MS and MPN [7,9]. Supporting this notion, both MS and MPN are treated with type 1 interferons, which have very potent antiviral and immunomodulating effects. Indeed
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br Prognosis The management of AML in
2019-04-19
Prognosis The management of AML in the elderly patient presents a significant challenge for hematologists. Careful evaluation of both patient and disease is required in each individual case to make optimal management decisions, and maximize the benefit to the patient. Apart from the extremely old
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Significant uncertainty remains about the precise vectors
2019-04-19
Significant uncertainty remains about the precise vectors, the plasticity of vector host-selection (ie, monkey human) and the exact location of vector exposure that results in human transmission of especially across different parts of Asia. In particular, uncertainty exists as to whether transmissio
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br Efforts to address malnutrition maternal and child
2019-04-19
Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man
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Atrial fibrosis is one of
2019-04-19
Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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orphan receptor br Perioperative risk assessment of thromboe
2019-04-19
Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical orphan receptor valve, chronic atrial fibrillation or venous thromboembolis
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br Discussion ATS is rare
2019-04-19
Discussion ATS is rare, and there are few reports of pregnant patients with this condition. Subbiah et al. [6] reported a case of pregnancy complicated with ATS in which ventricular ectopy was also decreased during pregnancy. The mechanism underlying the reduction of VA in pregnant patients with
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Introduction Classically increased cardiac fibrosis has been
2019-04-19
Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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