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En la segunda publicaci n
2019-04-20
En la segunda publicación, “Entrevista con don Carlos Pérez”, éste un ciudadano argentino ficticio recién llegado de Bogotá durante un viaje por Sudamérica, menciona pepstatin José María Rivas Groot a propósito de su “Estudio pre liminar”, en el Parnaso colombiano publicado en 1888 y los poetas reun
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Sin embargo la mayor a
2019-04-20
Sin embargo, la mayoría de los aventureros se quedó en la ensoñación, pues no logró hacerse de caudales, ni alcanzó encomiendas; de hecho, hacia 1540 y aun años después, el número de encomenderos en el gran Perú (hoy Perú, Bolivia y Ecuador) jamás rebasó los 500, indudablemente una minoría de la pob
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Finally it is highly interesting to note that human
2019-04-20
Finally, it is highly interesting to note that human endogenous retroviruses have been suggested to play a role in the etiology of both MS and MPN [7,9]. Supporting this notion, both MS and MPN are treated with type 1 interferons, which have very potent antiviral and immunomodulating effects. Indeed
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br Prognosis The management of AML in
2019-04-19
Prognosis The management of AML in the elderly patient presents a significant challenge for hematologists. Careful evaluation of both patient and disease is required in each individual case to make optimal management decisions, and maximize the benefit to the patient. Apart from the extremely old
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Significant uncertainty remains about the precise vectors
2019-04-19
Significant uncertainty remains about the precise vectors, the plasticity of vector host-selection (ie, monkey human) and the exact location of vector exposure that results in human transmission of especially across different parts of Asia. In particular, uncertainty exists as to whether transmissio
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br Efforts to address malnutrition maternal and child
2019-04-19
Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man
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Atrial fibrosis is one of
2019-04-19
Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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orphan receptor br Perioperative risk assessment of thromboe
2019-04-19
Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical orphan receptor valve, chronic atrial fibrillation or venous thromboembolis
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br Discussion ATS is rare
2019-04-19
Discussion ATS is rare, and there are few reports of pregnant patients with this condition. Subbiah et al. [6] reported a case of pregnancy complicated with ATS in which ventricular ectopy was also decreased during pregnancy. The mechanism underlying the reduction of VA in pregnant patients with
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Introduction Classically increased cardiac fibrosis has been
2019-04-19
Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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Much previous work highlights the rapid increases
2019-04-19
Much previous work highlights the rapid increases in DAH in the past decade, but in , Katherine Floyd and colleagues report that, in the case of tuberculosis, growth in domestic financing has been equally impressive. Their findings are convincing, especially in view of the fact that their study migh
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adipor1 The Zika virus epidemic is spreading
2019-04-18
The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil
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TRAF as a multi functional adaptor protein can be
2019-04-18
TRAF6, as a multi-functional adaptor protein, can be rapidly activated following Toll Like Receptor 4 (TLR4) and ligand recognition [39], [40], [41], and plays an important role in inflammatory responses. Increasing evidence implied that TRAF6 is closely related to CNS diseases [42], [43]. In cerebr
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br Methods br Results The clinical genetic electrocardiograp
2019-04-18
Methods Results The clinical, genetic, electrocardiographic, and electrophysiological characteristics of the study patients are shown in Table 1. Eight of the 45 patients were symptomatic, having a history of syncope (n=3) or aborted SCD (n=5). The remaining 37 patients were asymptomatic, alth
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br Conclusions br Conflict of interest
2019-04-18
Conclusions Conflict of interest Introduction Endless loop tachycardia (ELT) is a well-recognized complication of dual chamber pacing systems [1,2]. Recent pacemaker systems adopt algorithms of ELT termination given that ELT is generally maintained at the programmed upper tracking rate. The
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